Introduction

The FilterRG node in SciCraft is used in the process of removing, or down-weighting, noisy spots or arrays from the data set. There are several quality measures that can be used when deciding if a spot or an array should be kept out of, or down-weighted throughout the analysis:

The desired procedure is to give weights to the different spots, depending on the flag value they are give in the image analysis process. In practice 'bad' spots are given less weight and 'good' spots more weight. The R package limma, gives you the option of defining your own weight functions, depending on how strict you are. Typically, spots removed are given weights equal, or very close to zero.



Subsections
Bjørn Kåre Alsberg 2006-04-06